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Physical Pharmacy Classroom
The biological activity of drug in a body, in the ultimate sense, is the sum of molecular interactions such as transport, distribution, binding to its receptor, etc. all of which, in turn, are physical phenomena originating from the physicochemical properties of the individual molecules. physical pharmacy is a research area to study the macro-to-microscopic behaviours and properties of bioactive molecules. making use of the concepts from pure sciences and physical chemistry, and offering quanitative and rational backgrounds of drug actions at molecular level to other fields of pharmacy, physical phamacy is one field of pharmacy which has the final hope of making the whole world without diseases.


Under the proposition of understanding biological activities of drugs at molecular level, the members of our lab. are trying to elucidate 3d-structures and properties of bio-active molecules, and to find out the basics of molecular interactions between them. to study the physicochemical properties of drug molecules, we are using several approaches such as thermal analysis, spectroscopy, solubility measurement, etc. x-ray crystallography is our major tool to determine the 3d structure of bio-active molecules. computer-aided simulation by molecular mechanical, dynamical calculations is another important approach of our research with the final purpose of new drug design based on 3d-structure & acivity relationships.


Il Yeong Park, Ph.D. (parkiy@chungbuk.ac.kr)    Soo Jae Lee Ph.D. (sjlee@chungbuk.ac.kr)

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Analytical Chemistry Classroom
chemical analysis plays an essential role not only in pharmacutical science, chemistry, medicine, environmental science, geology, oceanography, material science, forensic science archeology, and a multitud of other fields. identifying the constituents of a substance is qualitative analysis, whereas analysis include qualitative and qualtative analysis of pharmaceutical preparations, materials associated with natural or artificial pharmaceutical resources, deal with quality control of pharmaceutical, assay method, also including also new development of assay methods and principles etc.


1) a novel ms spectroscopic studies of biologically important materials
2) investigation of novel immundmdduylatory compounds from basidomycetes
3) development of antitumor agents from natural resources
4) development of fibrous activated carbons and its applications
5) functional analysis of sphingolipid metabolites
6) regulation and evaluation of life-style disease by s1p
7) macromolecule analysis using various methods such as NMR, ITC, CD
8) antibody engineering


Yong-Moon Lee, Ph.D. (ymleefn@chungbuk.ac.kr)    Ji-Hun Kim, Ph.D.

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Pharmaceutics Classroom
pharmaceutics provides integral programs of manufacturing dosage forms, drug dosage regimens, biopharmaceutics and pharmacokinetics, concerning the courses of pharmaceutics, industrial pharmacy, pharmacokinetics and pharmacopeia. main research fields are i) the developement of new drug delivery systems for peptide and protein drugs using polymers, and ii) biological membrane transport, pharmacokinetic and bioequivalence studies for the new drug design. kun han (ph.d., professor) and youn bok chung (ph.d., associate professor) work for the laboratory.


1) pepetide and protein drug delivery system
2) bioadhesive polymer
3) drug delivery systems
4) biopharmaceutics and phmacokinetics for the new drug design
5) transport across the biological membranes such as hepatic and ocular epithelia
6) absorption, distribution, metabolism, excretion (adme) and bioequivalence study
7) systemic drug delivery system (micelle, liposome)


Youn Bok Chung, Ph.D. (chungyb@chungbuk.ac.kr)    Dae Hwan Shin, Ph.D. (dshin@chungbuk.ac.kr)

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Microbiology Classroom
pharmaceutics provides integral programs of manufacturing dosage forms, drug dosage regimens, biopharmaceutics and pharmacokinetics, concerning the courses of pharmaceutics, industrial pharmacy, pharmacokinetics and pharmacopeia. main research fields are i) the developement of new drug delivery systems for peptide and protein drugs using polymers, and ii) biological membrane transport, pharmacokinetic and bioequivalence studies for the new drug design. kun han (ph.d., professor) and youn bok chung (ph.d., associate professor) work for the laboratory.


1) mechanisms for the class i mhc-restricted antigen presentation 2) immune escape mechanisms of hepatitis c virus 3) structure-activity relationship of cc chemokines 4) immunodulators from natural products


Chong-Kil Lee, Ph.D. (cklee@chungbuk.ac.kr)    Suk-Gil Song Ph.D. (songs@chungbuk.ac.kr)

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Medical Chemistry Classroom
medical chemistry is an interdisciplinary research area incorporating synthetic organic chemistry, biochemistry, pharmacology, molecular biology and pharmaceutical chemistry in the search for better drugs. the effective treatment of patients with various diseases such as aids and cancer depends, to a great extent, on the ability of medicinal chemists to discover new drugs.


1) design and synthesis of new potential antitumor agents in several different classes: the research includes the design of agents based on the structures of naturally-occurring tumor inhibitors and topoisomerase inhibitors.
2) design and synthesis of new antioxidants as potential neuroprotectants
3) development of novel organic reaction methodology and its application to the efficient synthesis of key building blocks
4) total synthesis of biologically active natural products including alkaloids


Hee Soon Lee, Ph.D. (medchem@chungbuk.ac.kr)    Jae-Kyung Jung, Ph.D. (orgjkjung@chungbuk.ac.kr)

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