홈 > 대학원 > Lab of Pharmaceutical Microbiology & Immunology
홈 > 대학원 > Lab of Pharmaceutical Microbiology & Immunology
Chong-Kill Lee
Suk-Gil Song
Chong-Kill Lee
043-261-2826
cklee@chungbuk.ac.kr
Education & Career
1977-1981 B.S. Department of Pharmacy, Chungbuk National University, Korea
1981-1983 M.S. Department of Pharmacy, Seoul National University, Korea
1986-1990 Ph.D. Department of Microbiology and Immunology, University of Health Sciences/The Chicago Medical School, IL, USA
Professional Experience
1990-1994 Assistant Professor, College of Pharmacy, Chungbuk National University
1994-1999 Associate Professor, College of Pharmacy, Chungbuk National University
1996-1998 Visiting Fellow, Laboratory of Immunoregulation, NCI, Frederick, MD, USA
1999-present Professor, College of Pharmacy, Chungbuk National University
2009-2010 Dean, College of Pharmacy, Chungbuk National University
2010-2010 Vice President, The Korean Association of Immunologists (KAI)
2011-2011 President, The Korean Association of Immunologists (KAI)
2011-2012 Vice President, The Pharmaceutical Society of Korea
2013-present Editor-in-Chief of Immune Network, The official journal of KAI
Research Areas
Regulation of T cell responses via modulation of MHC-restricted antigen presentation
Efficient generation and use of regulatory dendritic cells
Fabrication and characterization of immunomodulatory & anti-cancer biodegradable nanoparticles
Selected Publications
Kim KH, Kim SH, Jung HH, Moon JH, Jeong SU, Yu K, Lee CK. (2018). Thapsigargin increases IL-2 production in T cells at nanomolar concentrations. Immune Netw. 18(4):e26.
Lee H, Lee Y, Kim J, An J, Lee S, Kong H, Song Y, Lee CK, Kim K. (2018). Modulation of the gut microbiota by metformin improves metabolic profiles in aged obese mice. Gut Microbes. 9(2):155-165.
Kim SH, Jung HH, Lee CK. (2018). Generation, characteristics and clinical trials of ex vivo generated tolerogenic dendritic cells. Yonsei Med J. 59(7): 807-815.
Lee, .J.H., Park, C.S., Jang, S., Kim, J.W.., Kim, S.H., Song, S., Kim, K., Lee, C.K. (2017). Tolerogenic dendritic cells are efficiently generated using minocycline and dexamethasone. Sci. Rep. 7:15087.
Shim, S.M., Song, E,J., Song, D., Lee, T.Y., Kim, D.J., Nam, J.H., Gwin, Jeong. D., Le, C.K., Kim, S.H., Kim, J.K. (2017). Nontoxic outer membrane vesicles efficiently increase the efficacy of an influenza vaccine in mice and ferrets. Vaccine. 35(30): 3741-3748.
Im, S., Kim, J.W., Kim, H.S., Park, C.S., Shin, E., Do, S.G., Park, Y.I., Lee, C.-K. (2016). Prevention of azoxymethane/dextran sodium sulfate-induced mouse colon carcinogenesis by processed Aloe vera gel. Int. Immunopharm. 40: 428-435.
Lee, Y.H., Im, S.A., Kim, J.W., Lee, C.K. (2016). Vanilloid receptor 1 agonist, capsaicin and resiniferatoxin, enhances MHC class I-restricted viral anigen presentation in virus-infected dendritic cells. Immune Netw. 16(4): 233-241.
Lee, Y., Im, S.A., Kim, J., Lee, S., Kwon, J., Lee, H., Kong, H., Song, Y., Shin, E., Do, S.G., Lee, C.-K., Kim, K. (2016). Modified Aloe polysaccharide restores chronic stress-induced immunosuppression in mice. Int. J. Mol. Sci. 17(10): 1660..
Kim, N., Park, C.S., Im, S.A., Kim, J.W., Lee, J.H., Park, Y.J., Song, S., Lee, C.-K. (2106). Minocycline promotes the generation of dendritic cells with regulatory properties. Oncotarget. 7(33): 52818-52831.
Im, S.A., Park, C.S., Lee, C.-K. (2016). Immunoaugmenting activity of acemannan, the polysaccharides isolated from Aloe vera gel. Kor. J. Pharmacogn. 47(2): 103-109.
Suk-Gil Song
043-261-2817
songs@chungbuk.ac.kr
Education & Career :
1986 B.S. College of Pharmacy, Chungbuk University, Korea
1989 M.S. Korea Advanced Institute of Science and Technology
1998 Ph.D. Korea Advanced Institute of Science and Technology
1998-2001 Visiting Scientist. National Cancer Institute, NIH
2005-2007 Assistant Dean, Collage of Pharmacy
Research Areas
Cell Division Cycle, Polo-like kinase
Cancer Development, Modulation of Cell Proliferation
Genome Stability, Spindle Checkpoint
Selected Publications
Lung tumor growth-promoting function of peroxiredoxin 6, FREE RADICAL BIOLOGY AND MEDICINE, 2013
Downregulation of Melanocyte-Specific Facultative Melanogenesis by 4-Hydroxy-3-Methoxycinnamaldehyde Acting as a cAMP Antagonist, JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2014
Baccatin III, a precursor for the semisynthesis of paclitaxel, inhibits the accumulation and suppressive activity of myeloid-derived suppressor cells in tumor-bearing mice, INTERNATIONAL IMMUNOPHARMACOLOGY, 2014
Resiquimod, a TLR7/8 agonist, promotes differentiation of myeloid-derived suppressor cells into macrophages and dendritic cells, ARCHIVES OF PHARMACAL RESEARCH, 2014
Identification of HLA-A2-restricted immunogenic peptides derived from a xenogenic porcine major histocompatibility complex, XENOTRANSPLANTATION, 2014
Suberoylanilide hydroxamic acid induces ROS-mediated cleavage of HSP90 in leukemia cells, CELL STRESS & CHAPERONES, 2015
Interleukin-32 gamma attenuates ethanol-induced liver injury by the inhibition of cytochrome P450 2E1 e-pression and inflammatory responses, CLINICAL SCIENCE, 2015
Decreased severity of collagen antibody and lipopolysaccharide-induced arthritis in human IL-32β overexpressed transgenic mice., Oncotarget, 2015
Minocycline promotes the generation of dendritic cells with regulatory properties, ONCOTARGET, 2016
Tolerogenic dendritic cells are efficiently generated using minocycline and dexamethasone, SCIENTIFIC REPORTS, 2017